Scientific Program

FINAL PROGRAM

Day 1 (Wednesday May 31):

Registration starts from 10:00

13:30 – 13:45	Opening remarks: Lukas Trantirek
13:45 – 14:05	Opening lecture: Jean-Louis Mergny - Quadruplexes are everywhere!
14:05 - 14:50	Meeting keynote lecture: Martin Gellert - G quartets: the pre-history and its consequences

SESSION 1 – Quadruplex structure

	Chair: Anh Tuan Phan
14:50 – 15:25	KL1: Janez Plavec - Fascinating NMR structures of tetrahelical DNA different from G-quadruplexes
15:25 – 15:45	L1: Claudia Sissi - Conformational profiling of G-quadruplex units in cKIT promoter as tool to drive the rational design of new chemotherapeutics
15:45 – 16:05	L2: Vojc Kocman - AGCGA-quadruplexes a novel tetrahelical structural family
16:05 – 16:35	Coffee break
	Chair: Anh Tuan Phan
16:35 – 16:55	L3: Jiri Sponer - Structural dynamics and folding of DNA quadruplexes: Theory and experiment.
16:55 – 17:15	L4: Peter Unrau - Converting a G-quadruplex based fluorophore binding aptamer into an efficient bimolecular fluorescent switch
17:15 – 17:35	L5: Jonathan B. Chaires - How POT1 unfolds G4 DNA
17:35 – 17:55	L6: Mikayel Aznauryan - Folding dynamics of G-quadruplex DNA in physiologically relevant milieu: moving towards in vivo
17:55 – 18:15	L7: Vitaly Kuryavyi - An unprecedented DNA structure with parallel- and antiparallel-stranded segments bridged by conjoined base triples
18:15 – 19:00	Poster flash presentations I
19:00 – 21:30	Poster session I with Welcome dinner

Day 2 (Thursday June 1)

SESSION 2 – G4 targets/ Quadruplex ligands

	Chair: Janez Plavec
9:00 – 9:35	KL2: Anh Tuan Phan - G-quadruplex structure, dynamics and recognition implications for the development of G-quadruplex ligands
9:35 – 9:55	L8: Concetta Giancola - Stability of G-quadruplexes and their ligand interactions: a thermodynamic insight.
9:55 – 10:15	L9: Ramon Vilar - Studying Ligand-Quadruplex DNA Interactions in Live Cells by Fluorescence Lifetime Imaging Microscopy
10:15 – 10:35	L10: Daniela Montesarchio - Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes
10:35 - 11:05	Coffee break
	Chair: Janez Plavec
11:05 – 11:40	KL3: Naoki Sugimoto - New targets of pharmaceutical drugs; Non-canonical DNA and RNA.
11:40 – 12:00	L11: Balci Hamza - A Single Molecule Approach to Study G-quadruplex, Protein, and Small Molecule Interactions
12:00 – 12:20	L12: Antonio Randazzo - DNA G-quadruplex interacting proteins: from identification to characterization
12:20 – 12:40	L13: Valerie Gabelica - A mass spectrometry insight into G-quadruplex folding and ligand binding
12:40 - 14:00	Lunch

	Chair: Antonio Randazzo
14:00 – 14:35	KL4: Stephen Neidle - Where we are with the development of G4 drugs in human cancer
14:35 – 14:55	L14: Marie-Paule Teulade-Fichou - Visualization strategies and molecular tools for probing the G4 genome.
14:55 – 15:15	L15: John Trent - Targeting the human telomere quadruplex system
15:15 – 15:35	L16: Carika Weldon -Specific G-quadruplex ligands regulate the alternative splicing of Bcl-X
15:35 – 16:05	Coffee break

SESSION 3A – Quadruplex nanotech and biotech

	Chair: Antonio Randazzo
16:05 – 16:40	KL5: Dipankar Sen - A new molecular tool to fish for G-quadruplexes in cells?
16:40 – 17:00	L17: Hiroshi Sugiyama - Chemical Biology of G-quadruplex
17:00 – 17:20	L18: Paula J.Bates - Antiproliferative G-Quadruplex Oligos: How do they REALLY work?
17:20 – 17:40	L19: Scarlett Dvorkin - High Throughput Tools for Whole Genome Quadruplex Characterization
17:40 – 18:25	Poster Flash Presentations II
18:25 – 21:30	Poster session II Wine and Cheese party

Day 3 (Friday June 2)

SESSION 3 A– Quadruplex nanotech and biotech / unusual DNA structures

	Chair: Jean-Louis Mergny
9:00 – 9:35	KL6: Itamar Willner - Quadruplex Nucleic Acids for Molecular Devices and Functional Materials
9:35 – 9:55	L20: Omer Lustgarten - Asymmetric G-Quadruplex DNA Scaffolds and their Application as Combinatorial Sensors and Molecular Security Systems
9:55 – 10:15	L21: Miroslav Fojta - Exploring DNA structure by electrochemical methods
10:15 – 10:35	L22: Andrea Tanzer - Prediction of RNA G4 Structures in The Light of Their Sequence Context
10:35 – 11:05	Coffee break

SESSION 3B – The i-motif corner

	Chair: Jean-Louis Mergny
11:05 – 11.025	L23: Zoe Waller - Adventures with the “other” strand: stabilising i-motif structures and effects of epigenetic modification
11.25 – 11.45	L24: Carlos González - I-motifs at neutral pH
11.45 – 12.10	Poster Flash Presentations III
12:10 – 13:40	Lunch

SESSION 4 – G4 biology

	Chair: Nancy Maizels
13:40 – 14:15	KL7: Sir Shankar Balasubramanian - Existence and consequences of G-quadruplex structures in DNA.
14:15 – 14:35:	L25:Cynthia J. Burrows - Gene Induction Activity of G4s in Promoters
14:35 – 14:55:	L26: Nora Calcaterra - G-quadruplexes: non-canonical DNA structures controlling life from the beginning
14:55 – 15:15	L27: Tracy Bryan - Implications of G-quadruplexes for human telomere maintenance mechanisms
15:15 – 15:35	L28: Guillaume Guilbaud - G-quadruplex replication and epigenome maintenance
15:35 – 16:05	Coffee break
	Chair: Nancy Maizels
16:05 – 16.25:	L29: Alain Nicolas - Role of G quadruplexes in genome instability
16.25 – 16.45:	L30: Giovanni Capranico - Modulation of R loops and DNA damage by G4 binders
16:45 – 17:05:	L31: Jens Kurreck - Proteomic Analysis of the Biological Function of RNA Guanine-Quadruplex Motifs in the 5’-UTR of mRNAs
17:05 – 17:25	L32: Vivekanandan Perumal - A G-quadruplex motif in the HBV genome enhances transcription and virion secretion
17:25 – 17:45	L33: Marie-Line Andreola - G-quadruplex nucleic acids in HIV-1: function and therapeutic applications
17:45 – 18:05	L34: Ilaria Frasson - G-quadruplex presence, conservation and location in all human viruses; a close-up on retroviruses and herpes viruses
18:05 – 18:50	Poster session III.
20:00 – 22:30	Gala dinner

Day 4 (Saturday June 3)

SESSION 4 – G4 biology

	Chair: Paula Bates
9:00 – 9:35	KL8: Nancy Maizels - G-quadruplexes in human health and disease
9:35 – 9:55	L35: Robin van Schendel - Dealing with G-quadruplexes that hamper ongoing DNA replication
9:55 – 10:15	L36: Marta Fay - G-quadruplexes under stress
10:15 – 10:35	L37: Danzhou Yang - Promoter G-quadruplexes: structure, function and diversity
10:35 – 11:05	Coffee break
	Chair: Paula Bates
11:05 – 11:25	L38: Pavel Ivanov - Diverse biology of RNA G-quadruplexes
11:25 – 11:45	L39: Samuel Rouleau - RNA G-Quadruplexes regulate the biogenesis and function of cancer related microRNAs
11:45 – 12:30	Closing – Awards ceremony
12:30 – 13:30	Lunch

Posters

Poster presentation

Please note that size of the poster board is A0, portrait oriented.

The posters will be displayed from Wednesday, 31^st of May till Saturday 3^rd of June. It is possible to hang the posters in the Poster session hall at the first floor of the hotel (please follow the signs) from 12:00 am, Wednesday May 31^st. Posters should be removed before 9:00 am, Saturday June 3^rd.

Poster session is scheduled as follows:

Poster session I: Wednesday, 31st May from 19:00 till 21:30, posters no. 1- 95,

Poster session II: Thursday, 1st June from 18:25 till 21:30, posters no. 96 - 191

Poster session III: Friday 2nd June from 18:05 till 18:50.

Only posters submitted to poster competition (P: 001, 002, 006, 008 009, 010, 011, 014, 019, 020, 021, 027, 028, 030, 038, 055, 057, 061, 063, 065, 071, 072, 076, 077, 082, 087, 089, 094, 095, 098, 104, 110, 116, 119, 124, 130, 132, 148, 151, 163, 166, 179, 180, 189)

Poster Flash Presentation

Only posters submited for students poster competition will be presented during Poster Flash Presentation.

List of posters

Org. No.	Surname	Name	Topic	Title
P001	Abdelhamid	Mahmoud	Unusual (non G4) nucleic acids	Cu+ stabilizes and induces cytosine-cytosine base pairs in i-motif DNA
P002	Abou Assi	Hala	Structure	Trapping G-quadruplex/i-Motif Intermediates of Human Telomeric DNA
P003	Amato	Jussara	Structure	Insights into G-quadruplex recognition by HMGB1 protein
P004	Andrałojć	Witold	Structure	Unraveling the structural basis for the exceptional stability of RNA G-quadruplexes capped by the GGU sequence at the 3’ terminus
P005	Armas	Pablo	Biology	Chaperoning RNA and DNA G-quadruplexes that control proto-oncogenes expression.
P006	Bakalar	Blaz	Structure	A minimal left-handed G-quadruplex motif
P008	Bansal	Varun	Biology	G-quadruplex in the promoter of proto-oncogene Bcl3 is essential for controlling the expression of Bcl3
P009	Bartolucci	Laura	Biology	G-quadruplex Nucleic Acids in HIV-1
P010	Baxter	Colette	Biology	The regulation of growth by G-Quadruplex dependant processes in the plant model species Arabidopsis thaliana.
P011	Bekova	Katerina	Unusual (non G4) nucleic acids	The G-hairpin formation propensity
P012	Beniaminov	Artemy	Ligands	Using of Porphyrin Derivatives for Study of G-quadruplexes within Double-Stranded DNA
P013	Birkedal	Victoria	Ligands	Folding and conformational heterogeneity of human telomeric G-quadruplexes following ligand binding
P014	Biswas	Banhi	Biology	Co-evolution of G-quadruplexes in viruses and the infected hosts
P015	Blondel	Marc	Biology	A yeast-based assay identifies a host cell protein required for the Epstein-Barr virus-encoded EBNA1 immune evasion through binding to G-quadruplexes of EBNA1 mRNA
P016	Bourdoncle	Anne	Unusual (non G4) nucleic acids	G-quadruplexes unfolding by proteins
P017	Brazda	Vaclav	Methodology	A novel H/D exchange mass spectrometry approach to assess protein interactions with quadruplex DNA
P018	Brazdova	Marie	Biology	G-quadruplexes as regulatory motifs in p53 world
P019	Brčić	Jasna	Structure	Two G-quadruplex structures formed by DNA oligonucleotide with GGGGCC repeats linked to ALS and FTD
P020	Carducci	Federica	Nanotech-Biotech	G4-based Hydrogels as a possible tool for protein crystallization
P021	Carvalho	Josué	Ligands	KRAS-22RT G-quadruplex stabilization by Acridine Orange derivatives
P022	Chakraborty	Gurudas	Nanotech-Biotech	Metal-Free DNA Structure and Catalytic Activity in Organic Solvents by Noncovalent Functionalization
P023	Chalikian	Tigran	Structure	Ionic Effects on G-quadruplex Stability
P024	Chatterjee	Subhrangsu	Biology	Arresting G-Quadruplex structure at LNC-X2 (Long Non Coding RNA–X2) promoter to inhibit Cancer Metastasis
P025	Chatterjee	Subhrangsu	Biology	Impediment of Quadruplex-mediated c-MYC transcription by Synthetic peptides via Stabilizing Pu27 quadruplex: a novel avenue in anti-cancer therapy
P026	Chen	Shuo-Bin	Ligands	A novel cell imaging assay for identifying NRAS RNA G-quadruplex ligands based on GTFH probe
P027	Chen	Jielin	Methodology	A Novel Method to Construct High-Activity G-quadruplex/hemin DNAzymes
P028	Chilka	Pallavi	Structure	Selective Recognition of G-Quadruplexes by Dimeric Carbocyanine Dyes
P029	Chorell	Erik	Ligands	Design and synthesis of molecular tools to study G4 structures
P030	Craven	Holly	Biology	G-quadruplexes in the parasitic platyhelminth Schistosoma mansoni: identification and anthelmintic suitability
P031	Cristofari	Camilla	Unusual (non G4) nucleic acids	EGFR promoter region: structural characterization of the C-rich sequence
P032	Croquette	Vincent	Biology	Real time unfolding of G-quadruplex by helicases and polymerases
P033	Cruz	Carla	Ligands	G-quadruplexes stabilization by phenanthroline-bis-oxazole ligands
P034	Dao	Thuan	Methodology	Enhancement of intrinsic fluorescence in G-quadruplexes: mechanism of excimer formation
P035	Das	Rabindra Nath	Ligands	Design, Synthesis, and Evaluation of 2,9 Bis[(substitutedaminomethyl) phenyl]-1,10-phenanthroline Derivatives as G-Quadruplex Ligands
P036	Das	Poulomi	Ligands	Interaction of Telomestatin derivatives with human telomeric DNA: Trapping of DNA in a parallel-stranded G-quadruplex conformation
P037	David	Aldana Paula	Biology	Novel transcriptional regulatory mechanism for a gene involved in craniofacial development: G-quadruplex modulation by a nucleic acid chaperone.
P038	De Magis	Alessio	Biology	G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells
P039	Defrancq	Eric	Biology	Topologically constrained G-quadruplexes: new tools for the identification of proteins partners
P040	Del Villar-Guerra	Rafael	Structure	Analysis of Circular Dichroism Spectra of G-Quadruplexes
P041	Dembska	Anna	Nanotech-Biotech	Spectroscopic study of fluorescent probes based on G-quadruplex oligonucleotides labeled with ethynylpyrenyldeoxyuridine
P042	Dembska	Anna	Unusual (non G4) nucleic acids	Hairpin integrated with i-motif domain containing a tricyclic cytosine analogue
P043	Demkovicova	Erika	Ligands	Analysis of Ebola virus derived G-quadruplexes and thiazole orange interactions
P044	Di Antonio	Marco	Methodology	Dynamic live cell imaging of single DNA G-quadruplexes with Light-Sheet Microscopy
P045	Di Primo	Carmelo	Structure	Structural basis of 93del dimerization with potassium and sodium cations
P046	Dickerhoff	Jonathan	Structure	The Butterfly Effect: Modified Nucleotides for Analyzing DNA and RNA Quadruplex Folds
P047	Doria	Filippo	Ligands	Naphthalene diimide Cu(II) Complex, a Selective Scissoring Tool for Quadruplex Nucleic Acids.
P048	Drevenšek-Olenik	Irena	Nanotech-Biotech	Tunable Thin-Film Structures of Lipophilic Guanosine Derivatives
P049	Dvořáková	Zuzana	Structure	Influence of naturally occurring damage on formation and stability of human telomere i-motif
P050	Džatko	Šimon	Structure	Characterization of Non-B DNA structures in complex environment of mammalian cells by in cell NMR spectroscopy
P051	Fleming	Aaron	Structure	Zika viral genomic RNA possesses G-quadruplexes are characteristic of the Flaviviridae family
P052	Lago	Sara	Biology	A new protocol for kinetic analysis of 1H6 monoclonal antibody and G-quadruplex nucleic acids using surface plasmon resonance biosensing
P053	Fu	Yan	Nanotech-Biotech	G-quadruplex and i-motif: Promising Candidates in Biosensing
P054	Funke	Andrea	Ligands	Calorimetric Studies for Dissecting the Energetics of Indolo[3,2-b]quinolines Binding to Parallel G-Quadruplexes
P055	Garajský	Martin	Unusual (non G4) nucleic acids	DNA G-hairpin
P056	Galer	Petra	Structure	G-quadruplex system in dynamic equilibrium triggered by (de)protonation reaction
P057	Garant	Jean-Michel	Methodology	G4RNA screener a motif independent identification of potential RNA G-quadruplexes
P058	Gargallo	Raimundo	Methodology	Study of conformational equilibria of G-quadruplex and i-motif structures by means of multivariate analysis
P059	Gazanion	Elodie	Biology	G-quadruplex-mediated regulation of malaria parasites virulence
P060	Giassa	Ilektra-Chara	Structure	Structure of a G-quadruplex in the Green Monkey c-kit promoter
P061	Götz	Silvia	Biology	Zuo1 - a novel G4-binding protein
P062	Granqvist	Lotta	Methodology	Monitoring of G-Quadruplex/Hairpin Transitions by 19F NMR Spectroscopy
P063	Griffin	Wezley	Structure	Recognition of G4DNA by Positive coactivator 4: An expanded model of DNA recognition by a transcriptional coactivator
P064	Grover	Jagdeep	Ligands	NOVEL PORPHYRIN-BASED PORTMANTEAU LIGANDS TARGETING GUANINE-QUADRUPLEXES (GQs) AS ANTICANCER AGENTS
P065	Gruen	Tassilo	Structure	Investigation of Promoter G-Quadruplex Folding Dynamics using Real-Time NMR-spectroscopy
P066	Gudanis	Dorota	Structure	Influence of chemical modification on RNA duplex-quadruplex hybrid formation.
P067	Haensel-Hertsch	Robert	Biology	G-quadruplex structures mark human regulatory chromatin
P068	He	Mingze	Biology	G4 quadruplexes in and near regulatory elements of maize genes involved in tissue development and altered transcriptional response to abiotic stresses
P069	Hubert	Sandrine	Structure	AFM-based single molecule force spectroscopy on bimolecular hybrid DNA/RNA G-quadruplexes
P070	Hudecek	Oldrich	Unusual (non G4) nucleic acids	Development of capturing technique for 5’-diphosphate RNA
P071	Hur	Jeong Hwan	Ligands	Identification of a new Z-DNA inducer using SYBR Green 1 as a B-to-Z transition sensor
P072	Iaccarino	Nunzia	Ligands	Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives
P073	Ishizuka	Takumi	Methodology	A multi-functional guanine derivative for studying DNA G-quadruplex structure in vitro and in living cells
P074	Islam	Barira	Structure	Propeller Loop Conformations of Human Telomeric Quadruplex in MD Simulations Carried out in Molecular Crowding Conditions
P075	Jamroskovic	Jan	Ligands	Evaluation of new G4 binding analogues based on compounds identified in high throughput screening
P076	Jodoin	Rachel	Biology	A 5’-UTR RNA G-Quadruplex structure affects both the cap-dependent and independent translation of BAG-1, an mRNA involved in colorectal cancer
P077	Jordan	Deondre	Unusual (non G4) nucleic acids	The secondary structure of CAGAGG repeats linked to replication fork collapse
P078	Jurečka	Petr	Methodology	New Force Fields for Quadruplex Simulations - Performance, Comparison and Challenges
P079	Juskowiak	Bernard	Nanotech-Biotech	Cation-sensitive fluorescent probes based on tetraplex DNA structures
P080	Kalliat Thazhathveetil	Arun	Nanotech-Biotech	Hole transport through G-quadruplexes
P081	Kaluzhny	Dmitry	Ligands	The third side chain of anthraquinone derivatives leads to an increase in affinity and selectivity for telomeric G4
P082	Karg	Beatrice	Structure	Tetrad Polarity Reversal And Exchange Dynamics of Single Residues in Monomolecular Quadruplexes
P083	Kejnovská	Iva	Structure	Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes
P084	Kejnovsky	Eduard	Biology	Effect of G-quadruplexes on expression of plant transposable elements
P085	Kirillova	Yuliya	Structure	Chiral anionic PNAs: triplex formation and binding to G4 targets
P086	Kosman	Joanna	Nanotech-Biotech	Modifications of peroxidase-mimicking DNAzymes
P087	Kotar	Anita	Ligands	NMR study of triangulenium optical probe binding to a G-quadruplex
P088	Krafčík	Daniel	Biology	ALT specific telomeric repeat variant remodels conformational properties of telomeric C-rich DNA
P089	Krafčíková	Michaela	Ligands	Monitoring DNA-ligand interactions using in cell NMR spectroscopy
P090	Kreuzmann	Denise	Biology	ARPC2 translation is mediated by a G-quadruplex-containing internal ribosome entry site and regulated by different 5´UTR splice variants
P091	Kumari	Romika	Biology	Prediction of translational pauses caused by pharmacological stabilization of G-quadruplexes using ribosome profiling
P092	Lah	Jurij	Structure	Why a single guanine-rich DNA sequence folds into different G-quadruplex structures?
P093	Lavergne	Thomas	Ligands	Studies of G-Quadruplexes/Ligands Interactions by Surface Plasmon Resonance and Bio-Layer Interferometry
P094	Lee	Chun-Ying	Biology	Systematic and quantitative analysis of G-quadruplex DNA folding and its effect on gene expression
P095	Lefebvre	Joel	Ligands	Visualization of G-quadruplex ligands by click-chemistry in cells
P096	Lexa	Matej	Methodology	Extensive exploration of G4 combinatorial space in potential quadruplex searches with imperfection-tolerant R/Bioconductor package PQSfinder improves results on experimental datasets
P097	Ličen	Matjaž	Nanotech-Biotech	Photoregulating the self-assembly of lipophilic guanosine derivatives in thin surface films
P098	Liu	Kim	Ligands	Evaluating bicyclic peptides as G-quadruplex ligands
P100	Ma	Yue	Ligands	Synthesis and evaluation of ligand for selective induction of topologies in telomeric G-quadruplex
P101	Macgregor	Robert	Structure	The curiously small molar volume of formation of tetra-molecular GQ's
P102	Maity	Arijit	Structure	Structure of an unprecedented quadruplex-duplex hybrid formed by the C9ORF72 hexanucleotide GGGGCC repeat
P103	Mandal	Soham	Ligands	Tuning Copper(II) mediated stabilization of pyridine modified tetramolecular G-quadruplexes
P104	Manna	Sudeshna	Structure	Probing Human Telomeric DNA Repeat in Cell Models Using Conformation-Sensitive Nucleoside Analogs
P105	Marecki	John	Biology	Immunofluorescent detection of G4DNA in yeast and mammalian cells
P106	Marsh	Thomas	Nanotech-Biotech	The use of G-Wires as a Supramolecular G-DNA Scaffold.
P107	Martin-Pintado	Nerea	Biology	Deciphering the molecular mechanisms that resolve G-quadruplex structures during DNA replication
P108	Marušič	Maja	Structure	In reverse: the effect of DNA sequence inversion on G-quadruplex folding
P109	Merrick	Catherine Jill	Biology	RecQ helicases and G4s affect virulence gene expression and genome stability in the human malaria parasite Plasmodium falciparum
P110	Miglietta	Giulia	Biology	Targeted gene therapy for pancreatic cancer: anthraquinone derivatives bind to G-quadruplex cluster in KRAS mRNA and suppress translation.
P111	Miyoshi	Daisuke	Ligands	A new photodynamic therapy targeting mRNA G4
P112	Mohammad	Jani Basha	Biology	S. pombe Pfh1 unwinds stably formed G-quadruplex DNA structures derived from evolutionarily conserved G-quadruplex motif containing regions in the fission yeast genome
P113	Mojzeš	Peter	Structure	Interquadruplex transitions of human telomeric sequences in K+ solutions under molecular crowding conditions and sub-melting temperatures
P114	Monchaud	David	Ligands	Ever smarter synthetic G-quartets
P115	Morales	Juan Carlos	Ligands	Synthesis, binding properties, cell uptake and cytotoxicity of G-quadruplex ligands Synthesis, binding properties, cell uptake and cytotoxicity of G-quadruplex modified with carbohydrates
P116	Mueller	Diana	Structure	Investigation of the Folding Kinetic of RNA G-Quadruplexes using Real-Time NMR
P117	Nadai	Matteo	Ligands	A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging
P118	Ngo	Khac Huy	Biology	Unfolding of human telomeric DNA and RNA G-quadruplexes by proteins UP1 and POT1
P119	Noothanaganti	Ashok	Structure	Fluorescence and X-ray Analysis of G-quadruplex Structures Using Dual-Purpose Nucleoside Probes
P120	Nowack	Julia	Ligands	Copper-induced Stabilization and Topology Switching in Unimolecular G-Quadruplexes
P121	O'Hagan	Michael	Ligands	A sweet cure for cancer? Carbohydrate-bearing ligands for G-quadruplex DNA
P122	Onel	Buket	Structure	The 3'-End of the PDGFR-ß Core Promoter Nuclease Hypersensitive Element Forms a Mixture of Two Unique End-Insertion G-Quadruplexes That Can Be Targeted by an Ellipticine Analog
P123	Paeschke	Katrin	Biology	Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability
P124	Pagano	Alessia	Ligands	Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
P125	Parker	Matthew	Biology	Two tetrad G Quadruplexes modulate expression and splicing of EXTENSIN genes in Arabidopsis thaliana
P126	Parkinson	Gary	Methodology	The Use of an RNA-binding Protein as a Crystallization Scaffold for G-rich RNA Quadruplexes
P127	Paulo	Alexandra	Ligands	New V-shape modular ligands: synthesis, biophysical, biochemical and in silico studies
P128	Petr	Marek	Biology	Tumor suppressor p53 binding to MYC G-quadruplex
P129	Pirota	Valentina	Ligands	NDI-PNA conjugates targeting G4 structures within HIV-1 LTR promoter
P130	Platella	Chiara	Ligands	Towards High Throughput Screening method to identify G4-selective ligands
P131	Podbevsek	Peter	Structure	Structure of dimeric G-quadruplexes originating from the KRAS promoter
P132	Powell	Barrett	Unusual (non G4) nucleic acids	Pursuit of the Crystal Structure of CAGAGG Repeats in DNA
P133	Pozmogova	Galina	Structure	A THF-based modification induces antiparallel to parallel switches in G4 DNA
P134	Pozmogova	Galina	Structure	CpG methylation in G4 and IM structures
P135	Prioleau	Marie-Noelle	Biology	Determinants of replication origins in vertebrate cells
P136	Prorok	Paulina	Biology	Functional analysis of G quadruplexes in metazoan DNA replication origins
P137	Punt	Philip	Ligands	Coordination Chemistry of imidazole based ligands in G-quadruplex structures
P138	Rajczak	Ewa	Ligands	The interaction between metallacrowns different type and human telomeric DNA sequence
P139	Raney	Kevin	Biology	Helicase-catalyzed unfolding of G-quadruplex nucleic acids
P140	Ravichandran	Subramaniyam	Structure	Stability and Regulatory Effects of Stem-loop Containing Parallel Quadruplexes in Human Gene Promoters
P141	Rigo	Riccardo	Structure	Dissecting the structural features of G-rich promoter region of EGFR oncogene
P142	Ryazanova	Olga	Ligands	Binding of cationic pheophorbide-a to Na+-containing 22-mer oligonucleotide of human telomeric repeat: a spectroscopic study.
P143	Rynes	Jan	Biology	Relationship between structure and function of a polymorphic G-quadruplex formed from Pu27 element in c-MYC promoter
P144	Římal	Václav	Structure	Thermal changes and concentration-dependent folding of GGGN repeat
P145	Saad	Mona	Biology	Dictyostelium discoideum: A new cellular model for G-quadruplexes studies
P146	Saha	Abhijit	Ligands	Topology Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in BrU-Substituted DNA
P147	Salgado	Gilmar	Structure	NMR Structure and Ligand Binding of a G-Quadruplex Forming Sequence Within the KRAS Proto-Oncogene Promoter Region
P148	Santos	Tiago	Ligands	Selective isolation of G-quadruplex parallel sequences with naphthalene amine affinity support
P149	Saranathan	Nandhini	Biology	A Potential role for G-Quadruplexes in Virus Recombination
P150	Sasaki	Shogo	Ligands	Synthesis and evaluation of a linear hexaoxazole as G-quadruplex stabilizing ligands
P151	Sauer	Markus	Biology	Regulation of Translation by G-quadruplex-resolving RNA Helicase RHAU
P152	Scalabrin	Matteo	Ligands	Affinity selection mass spectrometry screening of small molecules libraries for the binding to viral G-quadruplexes
P153	Schwindt	Eike	Biology	Functional Analysis of G-quadruplexes during Meiosis
P154	Sedghi Masoud	Shadi	Ligands	Synthesis of cyclic polyoxazole compound as i-motif binder
P155	Seergazhi Gopalan	Srivatsan	Methodology	Probing G-Quadruplex Structure and Recognition Using Multifunctional Nucleoside Probes
P156	Sica	Filomena	Structure	Structural basis for the recognition of human ?-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials
P157	Sierra Tornero	Sara	Ligands	G-quadruplex DNA interaction and biological activity of 1,10-phenanthroline derivatives
P158	Sigel	Roland	Structure	Isolation and characterization of various equilibrium structures of the BCL2 RNA G-4plex and their interaction with metal complexes
P160	Sket	Primoz	Structure	Cation induced dimerization of tetrameric G-quadruplex structure
P161	Sorefan	Karim	Biology	The function of G-quadruplexes in plants
P162	Spindler	Lea	Structure	Self-assembly and Diffusion of G-rich Oligonucleotides with 5'GC-ends
P163	Stadlbauer	Petr	Structure	Computational Folding of RNA G-Quadruplexes
P164	Steer	Isobel	Nanotech-Biotech	Real-time monitoring of interactions between naturally occurring proteins and DNA (or RNA) G-quadruplexes using Whispering Gallery Mode Resonators
P165	Stratmann	Lukas	Ligands	Metal-induced reversible stabilization of base modified G-quadruplexes
P166	Street	Steven	Ligands	Divalent carbohydrate G-quadruplex ligands with a remarkable selectivity profile
P167	Svehlova	Katerina	Ligands	Altered biochemical specificity of G-quadruplexes with mutated tetrads
P168	Školáková	Petra	Structure	Regulation of DNA i-motif formation via 5-methylation of cytosine residues: lessons learned from the epigenetic regulation of plant telomeric DNA
P169	Takenaka	Shigeori	Ligands	Cyclic perylene diimides derivatives as a new type of tetraplex DNA binder
P170	Terenzi	Alessio	Biology	Multiple G-quadruplex structures in KIT promoter: a systematic study
P171	Tokan	Viktor	Biology	Inhibitory effect of G4s originating from plant LTR retrotransposon on expression of reporter gene
P172	Tsukakoshi	Kaori	Nanotech-Biotech	Structural regulation of G-quadruplex-forming aptamers by a G-quadruplex ligand
P173	Urland	Viktoria	Unusual (non G4) nucleic acids	Towards a High-Throughput, microfluidics based screening platform for G-quadruplex binders
P174	Van Neste	Christophe	Biology	G-quadruplexes on the pivot point between low and high risk neuroblastoma
P175	Varizhuk	Anna	Unusual (non G4) nucleic acids	A G-clamp analogue for i-motif stabilization
P176	Verga	Daniela	Ligands	Comparison of benchmark G4 ligands: FRET melting assay vs G4-FID assay
P177	Viglasky	Viktor	Unusual (non G4) nucleic acids	Viral G-quadruplexes and their anticipated biological roles
P178	Vineyard	Warren	Biology	Connecting G-quadruplex formation to gene expression in plants
P179	Wang	Zenghui	Ligands	A photophysical study on the interaction between fluorescent platinum(II) complexes and a BCL-2 RNA G-quadruplex
P180	Wang	Yuqing	Ligands	Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction
P181	Wang	Baifan	Structure	A Reversible G-quadruplex pH Switch
P182	Winnerdy	Fernaldo Richtia	Structure	Interaction of (4n-1)-Guanine G-quadruplex with metabolite: NMR Structure of quadruplex-dinucleotide complex
P183	Wirmer-Bartoschek	Julia	Structure	NMR structure of a hybrid-2-G-quadruplex/ligand complex – structural changes in the capping region allow ligand binding
P184	Wright	Elise	Unusual (non G4) nucleic acids	Exploring the effect of epigenetic modifications on i-motif stability
P185	Yamaoki	Yudai	Structure	Invention of RNA aptamer and ribozyme whose activities switch on in response to potassium ion via G-quadruplex formation
P186	Yoneda	Juliana	Structure	Anisotropy of Guanosine-based hydrogels detect by SAXS
P187	You	Huijuan	Biology	Effects of RHAU helicase on G4 stability during the ATPase cycle
P188	Zaccaria	Francesco	Structure	The Role of Alkali Metal Cations in the Stabilization of Guanine Quadruplexes: Why K+ is the best.
P189	Zens	Valerie Christine	Structure	Quantitative formation of monomeric G-quadruplex DNA from higher order structures
P190	Zheng	Simin	Biology	Intronic non-coding RNA mediates targeting of AID to DNA
P191	Zhou	Jun	Structure	Position-dependent Effects of Ribose G-quartets in G-quadruplexes